The void at the corner of Greenwich and Harrison Streets, left by the sudden departure of Yaffa’s Café and Tea Room, will be filled with a very different neighborhood fixture. The owners of MaryAnn’s, now at West Broadway and Reade Street, hope to move their Mexican-style eatery to the space that, for 25 years, had been home to the eccentrically appointed bar and restaurant.

A manager at MaryAnn’s, who asked not to be named, said the move could happen as early as next April. The owner, Eddy Globokar, is scheduled to appear before Community Board 1’s Tribeca Committee on Nov. 18 in the hopes of securing a liquor license for the new location. He has not returned calls seeking comment.

Globokar opened the Tribeca outpost in 1999, but is moving out of the West Broadway location due to plans by the owners of the Cosmopolitan Hotel to raze the squat, two-story stucco building that houses the restaurant and build a six-story addition adjacent to the hotel.

MaryAnn’s got its start in 1986, at the corner of 8th Avenue and 16th Street in Chelsea. Over the years, it has built itself up into a mini-chain of cantina-style restaurants, with three locations in Manhattan, one in Connecticut and one in Westchester.

Many in Tribeca were left stunned in August, when Yaffa Faro suddenly decided to close her restaurant-bar. The day after the bar served its last drink, on Aug. 29, Faro told the Trib that she depends on profits from the summer and her outdoor café to get through the winter, when the bar and tearoom next door operate at a loss.

“This summer I made no money,” she said, citing the constant rain, and the construction outside on Harrison Street. “I’m not going to mortgage my house. I’m not going to do that.”